Aging may be inevitable, but why not take steps to make the process as efficient as possible by incorporating nutritional supplements to help along the way. There are several exciting new products on the market that have the potential to do just that. You've probably heard of one of the critical ingredients - resveratrol - a plant polyphenol commonly found in red wine.1 Reported health benefits regarding plant polyphenols include positive effects on the cardiac system, neurological system, and cancer suppression.*1

Another healthy aging ingredient is nicotinamide riboside (NR).* NR is an intermediate to NAD+ (meaning the body converts NR to NAD+), which is essential in repairing and maintaining genomic integrity and plays a vital role in many diseases such as type 2 diabetes, cancer, cardiovascular diseases, neurodegenerative diseases, and pro-inflammatory diseases.*2 NR supplementation increases NAD+ levels which are essential activators of sirtuin.*2

What is sirtuin, and what role does it play in “healthy aging”?

You're probably asking, what is sirtuin? Sirtuin is an anti-oxidant enzyme that depends on NAD+ to function, and sirtuin responds to nutritional and environmental stressors.* These stressors could include fasting, ionizing radiation, DNA damage, oxidative stress, and more.*2

Unfortunately, studies show that sirtuin activity declines with age, so supplementation with products that increase its activity can help make this enzyme more available for use.* Supplementation with NAD+ intermediaries (resveratrol and NR) can increase NAD+ levels, increasing sirtuin activity.*2 In fact, one study stated that resveratrol is "the most potent activator (of sirtuin)...."1

What products contain these "healthy aging" ingredients for supplementation?

Thorne's ResveraCel® supplement is an excellent source of these vital components to healthy aging*. This product features both of the essential elements discussed in this article, resveratrol and nicotinamide riboside (NR) (as well as other cofactors).3

Where can I get ResveraCel®?

ResveraCel® is available from our online dispensary and can be delivered directly to you! Click Here to get these health-benefiting supplements.*

Not sure if ResveraCel® is right for you? Schedule an appointment with us today! Click Here to book.

1. Howitz KT, Bitterman KJ, Cohen HY, Lamming DW, Lavu S, Wood JG, Zipkin RE, Chung P, Kisielewski A, Zhang LL, Scherer B, Sinclair DA. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature. 2003 Sep 11;425(6954):191-6. DOI: 10.1038/nature01960. Epub 2003 Aug 24. PMID: 12939617.
2. Imai S, Guarente L. NAD+ and sirtuins in aging and disease. Trends Cell Biol. 2014 Aug;24(8):464-71. DOI: 10.1016/j.tcb.2014.04.002. Epub 2014 Apr 29. PMID: 24786309; PMCID: PMC4112140.
3. https://thor.ne/Qdq9y

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